C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 29/00 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2705583
Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
L'invention concerne des dérivés d'amide de l'acide 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylique qui présentent un bon effet d'inhibition sur l'interaction des CAM (molécules d'adhésion cellulaire) et des intégrines leucocytaires et sont donc utiles dans le traitement d'une maladie inflammatoire.
Barbosa Antonio Jose Del Moral
Bentzien Joerg Martin
Brunette Steven Richard
Chen Zhidong
Cogan Derek
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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