Derivatives of 3-amino-1,2-propanediol

C - Chemistry – Metallurgy – 07 – D

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260/542.3, 260/5

C07D 317/22 (2006.01) C07D 205/04 (2006.01) C07D 265/22 (2006.01) C07D 303/22 (2006.01)

Patent

CA 1192221

Abstract Derivatives of 3-amino-1,2-propanediol of the formula Image (I) in which R11 represents polyhydroxy-lower alkyl, cycloalkyl-lower alkoxy-lower alkyl, lower alkylsulphonyl- amino bonded in the 4-position or 1-lower alkylcarbamoyl- 2-vinyl bonded in the 4-position, and alk represents a radical of the formula -CH2-CH2- or Image and salts of such compounds, processes for their manufac- ture, medicaments that contain the novel compounds, and their use as blockers of adrenergic .beta.-receptors for the treatment of Angina pectoris and heart rhythm disorders and as agents for reducing blood pressure.

383714

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