C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/224, 260/264
C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)
Patent
CA 1291758
IN THE CANADIAN PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: Derivatives of 3-imino-pyridazine, process for obtaining them and pharmaceutical composi- tions containing them in the names of: Camille Georges WERMUTH, Gilbert SCHLEWER, Michel HEAULME assigned to: SANOFI ABSTRACT OF THE DISCLOSURE The invention relates to derivatives of 2,3- dihydro 3-imino-pyridazine responding to general formula: (I) Image in which: - A represerts an atom of oxygen or of sulfur; - R1 represents a lower alkyl group, or an aromatic group selected from: . the phenyl group; . the phenyl groups mono- or poly-substituted by a halogen group, a lower alkyl group, a lower alkoxy group, a nitro group, a hydroxy or methylene- dioxy group; . the naphthyl group; . the furyl group; . the thienyl group or the pyridyl group; - R2 and R3 each designate independently hydrogen or a lower alkyl group; a phenyl group, or R2 and R3, taken together, constitute, with the 2 atoms of the pyridazinic cycle to which they are bonded, a benzene ring, and their pharmaceutically acceptable salts. Application: antidepressants or psychotonics.
521371
Heaulme Michel
Schlewer Gilbert
Wermuth Camille G.
Heaulme Michel
Schlewer Gilbert
Sim & Mcburney
Societe Anonyme Sanofi
Wermuth Camille G.
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