Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid...

Details Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid... Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid...

C - Chemistry, Metallurgy

07

D

167/208, 260/278

C07D 417/06 (2006.01) A61K 31/425 (2006.01) C07D 417/14 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2009709

ABSTRACT Compounds of general formula I Image (I) in which X represents a C1-C7 alkoxy group, an amino group, the residue of a primary or secondary aliphatic amine having 1-8 carbon atoms possibly containing at least one double and/or triple bonds, of a primary aralchylamine, of a cyclic aliphatic amine having 4-8 carbon atoms which are possibly interrupted by an atom of oxygen; R may be H or a C1-C8 alkyl, R is H or an alkyl group having 1 or more atoms of carbon. Pharmaceutical compositions containing these compounds, and use thereof for the preparation of pharmaceutical specialties useful for treating immune defense deficiencies, autoimmunity disorders and ageing processes.

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