Derivatives of 4-aminoquinoline and their use as medicaments

Details Derivatives of 4-aminoquinoline and their use as medicaments Derivatives of 4-aminoquinoline and their use as medicaments

C - Chemistry, Metallurgy

07

D

167/226, 260/281

C07D 215/42 (2006.01) A61K 31/47 (2006.01) C07D 215/44 (2006.01)

Patent

CA 1308106

Abstract Compounds of structure (I) Image ( I ) in which R1 is hydrogen, C1-6alkyl, C1-6alkoxylC1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylC1-6alkyl, phenyl, phenylC1-6alkyl, the phenyl groups being optionally substituted; R2 is C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-6alkyl, phenyl, phenylC1-6alkyl or phenyl substituted by 1-3 radicals selected from C1-6alkyl, C1-6alkoxy, amino C1-6alkylthio, halogen, cyano, hydroxy, carbamoyl, carboxy, C1-6alkanoyl, trifluoromethyl and nitro; R3 is C1-6alkyl, phenyl, C1-6alkoxy, C1-6alkylthio, C1-6alkanoyl, amino, C1-6alkylamino, di-C1-6alkylamino, halogen, trifluoromethyl or cyano; and n is 0, 1 or 2, or a pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy for the inhibition of gastric acid secretion.

545915

Affiliated with

Also associated with

Rating

Derivatives of 4-aminoquinoline and their use as medicaments does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Derivatives of 4-aminoquinoline and their use as medicaments, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Derivatives of 4-aminoquinoline and their use as medicaments will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1254789