C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/230.58
C07H 17/04 (2006.01)
Patent
CA 1216287
ABSTRACT OF THE DISCLOSURE This invention relates to novel 4'-demethyl-4- epipodophyllotoxin derivatives represented by the general formula (I), and salts thereof: Image (I) wherein R is a lower alkyl group, and X1 and X2 are independently a hydroxyl group or an amino group, the one being an amino group and the other being a hydroxyl group. These novel derivatives have a high carcinostatic activity and a relatively high water solubility and hence are expected to be useful as carcinostatics.
459897
Kondo Shinichi
Nishimura Yoshio
Takeuchi Tomio
Takita Tomohisa
Tanaka Wataru
Marks & Clerk
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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