Derivatives of 4-(thio- or...

C - Chemistry – Metallurgy – 07 – D

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C07D 409/04 (2006.01) A61K 31/4535 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01) C07D 421/04 (2006.01)

Patent

CA 2462416

The present invention relates to derivatives of 4-(Thio- or Selenoxanthene-9- ylidene)-piperidine or acridine of the Formula (I) and pharmaceutically acceptable salts thereof, use of these compounds as a medicament and for the manufacture of a medicament for treatment of a disease state which can be alleviated by treatment with a 5-HT2B antagonist.

La présente invention concerne des dérivés de 4-(thio- ou sélénoxanthène-9-ylidène)-pipéridine ou acridine, ou des sels pharmaceutiquement acceptables desdits dérivés. Elle concerne l'utilisation de ces composés comme médicament ou pour la fabrication d'un médicament destiné au traitement d'un état pathologique qui peut être atténué par un traitement mettant en oeuvre un antagoniste de 5-HT2B.

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