C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 275/34 (2006.01) A61K 31/205 (2006.01) A61K 31/66 (2006.01) A61P 3/10 (2006.01) C07C 235/20 (2006.01) C07C 275/16 (2006.01) C07C 275/24 (2006.01) C07F 9/54 (2006.01)
Patent
CA 2658797
The invention provides a new class of compounds capable of inhibiting carnitine palmitoyl transferase (CPT) having formula (I). The invention also relates to pharmaceutical compositions, which comprise at least one new compound according to the invention, and their therapeutic use in the treatment of hyperglycaemic conditions such as diabetes and the pathologies associated with it, such as for example congestive heart failure and obesity.
Cette invention concerne une nouvelle classe de composés de formule (I) capables d'inhiber la carnitine-palmitoyle-transférase (CPT). L'invention concerne également des compositions pharmaceutiques comprenant au moins un nouveau composé selon l'invention, et l'utilisation thérapeutique de telles compositions dans le cadre du traitement d'états hyperglycémiques tels que le diabète et les pathologies associées, par exemple l'insuffisance cardiaque congestive et l'obésité.
Conti Roberto
Dell'uomo Natalina
Giannessi Fabio
Tassoni Emanuela
Tinti Maria Ornella
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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