Derivatives of 5-amino-4, 6-disubstituted indole and...

Details Derivatives of 5-amino-4, 6-disubstituted indole and... Derivatives of 5-amino-4, 6-disubstituted indole and...

C - Chemistry, Metallurgy

07

D

C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61P 25/08 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2696012

This invention provides compounds of formula I where the dashed line represents an optional double bond; where R1 is phenyl, naphthyl, pyridyl, pyrimidyl, pyrrolyl, imidazolyl, pyrazyl, furyl, thienyl, oxazolyl, isoxazolyl, thiazolyl, or isothiazolyl, optionally substituted, and other substituents are defined herein. Such compounds are potassium channel modulators.

L'invention concerne des composés de formule I où la ligne en pointillé représente une double liaison facultative : où R1 est un phényle, naphtyle, pyridyle, pyrimidyle, pyrrolyle, imidazolyle, pyrazyle, furyle, thiényle, oxazolyle, isoxazolyle, thiazolyle, ou isothiazolyle, facultativement substitué et d'autres substituants sont tels que définis ici. De tels composés sont des modulateurs des canaux potassiques.

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