Derivatives of [6,7-dihydro-5h-imidazo[1,2-.alpha.]...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/4164 (2006.01) A61P 37/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2504219

Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]- propionamide. A compound of formula (I), which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

L'invention concerne des dérivés de [6,7-dihydro-5<I>H</I>-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide qui ont un bon effet inhibiteur sur l'interaction des molécules d'adhésion cellulaire et des leucointégrines et sont par conséquent utiles dans le traitement de maladies inflammatoires.

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