Derivatives of 9-(2-hydroxyethoxymethyl)guanine

Details Derivatives of 9-(2-hydroxyethoxymethyl)guanine Derivatives of 9-(2-hydroxyethoxymethyl)guanine

C - Chemistry, Metallurgy

07

D

260/242.3

C07D 473/02 (2006.01) C07D 473/00 (2006.01)

Patent

CA 1208637

ABSTRACT Compounds of the general formula Image (I) (wherein X represents an oxygen or sulphur atom R1 represents a hydroxy or amino group R2 represents a hydrogen atom or a group of formula -CH2OR3a and R3 and R3a which may be the same or different, each represents an amino acid acyl radical) and physiologically acceptable salts thereof are useful for the treatment of viral infections and have been found to have a surprisingly high water-solubility which renders them of value in the formulation of aqueous pharmaceutical preparations. Processes for preparing the compounds are described.

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