Derivatives of adipogenesis inhibitory factor, their...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/24 (2006.01) A61K 38/20 (2006.01) C07K 14/54 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01) C12P 21/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094177

ABSTRACT The present invention relates to derivatives of adipogenesis inhibitory factor (AGIF) which are equivalent to mature AGIF lacking from 2 to 9 of the N-terminal amino acids, as well as to nucleic acid coding for such derivatives, vectors and host cells containing such nucleic acid and methods for the production of such derivatives. Also claimed is the use of derivatives of AGIF which are equivalent to mature AGIF lacking from 1 to 9 of the N-terminal amino acids as therapeutic agents against cytopenia and morbid obesity.

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