Derivatives of apf and methods of use

A - Human Necessities – 61 – K

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A61K 38/14 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2734325

Derivatives of bladder epithelial antiproliferative factor and methods of using them are disclosed. In specific embodiments, the glycopeptide compositions are useful for the treatment and/or prevention of medical conditions, including cancer. In other embodiments, there are compositions and methods related to treatment of bladder conditions. In particular embodiments, the glycopeptide comprises D-pipecolic acid or L-pipecolic acid.

La présente invention concerne des dérivés d'un facteur antiprolifératif épithélial de vessie et des méthodes d'utilisation de ceux-ci. Dans des modes de réalisation spécifiques, les compositions glycopeptides sont utiles dans le traitement et/ou la prévention d'états pathologiques, y compris le cancer. Dans d'autres modes de réalisation, l'invention concerne des compositions et des méthodes afférentes destinées au traitement d'affections vésicales. Dans des modes de réalisation particuliers, le glycopeptide comprend un acide D-pipécolique ou un acide L-pipécolique.

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