Derivatives of benzoxazepine and benzazepine having...

Details Derivatives of benzoxazepine and benzazepine having... Derivatives of benzoxazepine and benzazepine having...

C - Chemistry, Metallurgy

07

D

260/241.1, 260/2

C07D 487/04 (2006.01) C07D 241/08 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1238320

Abstract A compound of formula (I): Image (I) in which R is optionally substituted phenyl; C3-8 cycloalkyl; C5-8 cycloalkenyl; C1-8 alkyl which may be straight or branched;C2-8 alkenyl which may be straight or branched: 5- or 6- membered heterocyclyl; or optionally sustituted phenyl C1-4 alkyl, each of Y and Z, which may be the same or different, is oxygen or sulphur; and X is -CH2- or oxygen, a process for the preparation of such compounds and their use in human and veterinary medicine. The compounds of the invention have useful anthelmintic activity, particularly against tapeworm.

458877

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