Derivatives of .beta.,.beta.-dimethyl-4-piperidineethanamine...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 211/26 (2006.01) A61K 31/445 (2006.01) C07D 211/34 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2163001

The present invention concerns .beta.,.beta.-dimethyl-4-piperidine- ethanamine compounds of the formula: Image (I) (wherein groups R1 to R3 are defined as indicated in the description), and addition salts thereof. It also concerns a process for their preparation and their therapeutic use as inhibitors for the cholesterol biosynthesis, in particular asepoxysqualene cyclase inhibitors, for obtaining an as hypocholesterolemic, hypolipemic, antiatheromatic and/or antifungal drug.

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