C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2402721
The present invention provides synthetic compounds, which are derivatives of the breast cancer antigen her-2 (amino acid residues 774 to 782), antibodies that recognize and bind to these compounds, polynucleotides that encode these compounds, and immune effector cells raised in response to presentation of these epitodes. The invention further provides methods for inducing an immune response and administering immunotherapy to a subject by delivering the compositions of the invention.
La présente invention concerne des composés de synthèse, des anticorps qui reconnaissent et se lient auxdits composés, des polynucléotides codant lesdits composés et des cellules effectrices de l'immunité qui se forment en réaction à la présentation de ces épitopes. L'invention concerne également des méthodes visant à induire une réponse immunitaire, ainsi que des méthodes d'immunothérapie consistant à administrer les compositions selon l'invention.
Borden Ladner Gervais Llp
Genzyme Corporation
LandOfFree
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