Derivatives of c-076 compounds

Details Derivatives of c-076 compounds Derivatives of c-076 compounds

C - Chemistry, Metallurgy

12

P

195/109, 260/233

C12P 17/06 (2006.01) A23K 1/17 (2006.01) A61K 31/365 (2006.01) C07D 313/06 (2006.01) C07D 493/20 (2006.01) C07H 19/01 (2006.01) C12P 17/18 (2006.01) C12P 19/62 (2006.01)

Patent

CA 1160169

ABSTRACT OF THE DISCLOSURE There are disclosed certain new derivatives of C-076 compounds which have been isolated from the fermentation broth that produced the original C-076 compounds. The compounds retain the C-076 16- membered cyclic backbone, however, the groups attached thereto are considerably modified from the original C-076 compounds. The new compounds have been found to retain the biological activity of the parent C-076 compounds. The compounds are thus potent anti- parasitic agents and compositions and methods for such uses are also disclosed.

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