Derivatives of camptothecin for use in treating cancer

Details Derivatives of camptothecin for use in treating cancer Derivatives of camptothecin for use in treating cancer

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2244698

Derivatives of camptothecin are disclosed and are represented by general formula (I), wherein when R2 is H, R1 is a C2-C4 alkyl group, a C6-C15 alkyl group, a C3-C8 cycloalkyl group, a C2-C15 alkenyl group or a C2-C15 epoxy group; and when R2 is a nitro group, R1 is a C1-C15 alkyl group, a C2-C15 alkenyl group, a C3-C8 cycloalkyl group, or an epoxy group. Processes for making these derivatives and for using them in cancer treatment are also disclosed.

Dérivés de camptothécine de formule générale (I), dans laquelle R2 est H, R1 est un groupe alkyle en C2-C4, un groupe alkyle en C6-C15, un groupe cycloalkyle en C3-C8, un groupe alcényle en C2-C15 ou un groupe époxy en C2-C15; et lorsque R2 est un groupe nitro, R1 est un groupe alkyle en C1-C15, un groupe alcényle en C2-C15, un groupe cycloalkyle en C3-C8 ou un groupe époxy. Sont également décrits de procédés permettant de réaliser ces dérivés et d'utiliser les produits obtenus dans le traitement du cancer.

Affiliated with

Also associated with

Rating

Derivatives of camptothecin for use in treating cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Derivatives of camptothecin for use in treating cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Derivatives of camptothecin for use in treating cancer will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1550517