Derivatives of cephalosporine, and their preparation

C - Chemistry – Metallurgy – 07 – D

Patent

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260/101, 260/244

C07D 498/04 (2006.01) C07D 501/24 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1197233

PRECIS DE LA DIVULGATION: L'invention concerne un procédé pour la préparation de dérivés de la céphalosporine de formule générale (I) dans laquelle R' représente un radical carboxy protégé, Hal représente un atome d'halogène, X1 représente un atome de soufre ou d'oxygène ou un radical sulfinyle et R représente un radical acyle ou un protecteur d'amine; et les dérivés ainsi obtenus. Ces nouveaux produits sont notamment utilisables comme intermédiaires pour la prépa- ration de médicaments antibactériens du groupe des céphalosporines. (I) Image

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