C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
260/460.7
C07F 9/10 (2006.01) C07F 9/09 (2006.01)
Patent
CA 1244462
Abstract The invention relates to new triphenylmethyl derivatives of sn-glycero-3-phosphocholine and sn-glycero- 3-phosphaethanolamine of the general formula Image I in which T denotes a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, and the radicals R1, R2 and R3 either are identical and each represent a methyl group, or are different, in which case two of the radicals R1, R2 and R3 always denote hydrogen, and the third radical represents a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, a process for their preparation, and their use for the preparation of chemically defined pure enantiomeric 1,2- diacyl-sn-glycero-3-phosphocholines and 1,2-diacyl-sn- glycero-3-phosphoethanolamines which are substituted in positions 1 and 2 of the glycerol, independently of one another, by different acyl radicals.
481204
Hermetter Albin
Paltauf Friedrich
Chemie Linz Aktiengesellschaft
Riches Mckenzie & Herbert Llp
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