Derivatives of gp160 and vaccines based on gp160 or a...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/49 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) C07K 14/16 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2092827

2092827 9206113 PCTABS00011 This invention provides novel, substantially uncleavable forms of gp160, and vaccine formulations containing gp160 or a derivative thereof, adjuvanted with 3-D Mpl. The compositions are useful for the immunotherapeutic and immunoprophylactic treatment of HIV infections.

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