Derivatives of hypoestoxides for the treatment of malaria

A - Human Necessities – 61 – K

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A61K 31/336 (2006.01) A61K 45/06 (2006.01) A61P 33/06 (2006.01)

Patent

CA 2742824

Novel diterpene compounds, in particular, hypoestoxide- related compounds, are provided in pure form or as contained in the native plant source, for treatment and prophylaxis of cancer, inflammatory diseases, hyperlipidemias, malaria, and diabetes mellitus. Embodiments also pertain to methods for using the hypoestoxide-related compounds to treat various diseases and symptoms associated with those diseases.

La présente invention concerne de nouveaux diterpènes, en particulier des composés apparentés aux hypoestoxydes, sous forme pure ou contenus dans le produit végétal originel, dans le traitement prophylactique et thérapeutique du cancer, des maladies inflammatoires, des hyperlipidémies, du paludisme et du diabète sucré. Les modes de réalisation concernent également des méthodes d'emploi de composés apparentés aux hypoestoxydes dans le traitement de diverses pathologies et des symptômes associés à ces pathologies.

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