Derivatives of imidazole, their preparation and utilisation,...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/64 (2006.01) A61K 31/415 (2006.01) C07C 17/00 (2006.01) C07C 45/63 (2006.01) C07C 47/24 (2006.01) C07D 233/54 (2006.01)

Patent

CA 1273942

ABSTRACT Derivatives of imidazole corresponding to formula I Image wherein X1, X2, Y1 and Y2, whether or not identical, can have different significancies, R1 is hydrogen, a methyl or phenyl group, R2 and R3, whether or not identical, represent hydrogen, a hydroxyl, alkyl or alkoxy group, it being possible for R1 and R2 together to represent a carbon-carbon bond, R4 and R5, whether or not iden- tical, being hydrogen or alkyl, and the tautomers and salts of these compounds, also the pharmaceutical com- positions containing them. The compounds are endowed with .alpha.2-blocking and/or anti- convulsive activities and are utilisable as therapeutic agents for man.

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