Derivatives of laspartomycin and preparation and use thereof

Details Derivatives of laspartomycin and preparation and use thereof Derivatives of laspartomycin and preparation and use thereof

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 38/12 (2006.01) A61K 47/44 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) C07K 1/14 (2006.01) C07K 7/08 (2006.01) C07K 9/00 (2006.01) C07K 11/02 (2006.01) C12N 1/02 (2006.01) C12P 21/00 (2006.01) C12P 21/04 (2006.01) C12P 39/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2450747

The present invention provides laspartomycin core peptides, laspartomycin core peptide derivatives, antimicrobial laspartomycin derivatives, methods for making laspartomycin core peptides, methods for making laspartomycin core peptide derivatives, methods for making antimicrobial laspartomycin derivatives, pharmaceutical compositions of antimicrobial laspartomycin derivatives, methods of inhibiting microbial growth and methods for treating and/or preventing microbial infections in a subject.

L'invention concerne des peptides noyau de laspartomycine, des dérivés de ces derniers, des dérivés antimicrobiens de laspartomycine, des procédés de production des peptides noyau de laspartomycine, des procédés de production des dérivés des peptides noyau de laspartomycine, des procédés de production des dérivés antimicrobiens de laspartomycine, des compositions pharmaceutiques de dérivés antimicrobiens de laspartomycine, des procédés d'inhibition de croissance microbienne et des méthodes de traitement et/ou de prévention d'infections microbiennes chez un sujet.

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