Derivatives of muramyl-peptides and steroids having...

C - Chemistry – Metallurgy – 07 – K

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C07K 9/00 (2006.01) A61K 9/127 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1257584

ABSTRACT Derivatives of muramyl-peptides and steroids having macrophage-activating properties The inveniton relates to compounds resulting from a covalent conjugation of the muramyl-peptide and the steroid particularly with membranal tropism, such as cholesterol, a precursor of its bio- synthesis , or a steroid which is derived therefrom including a hydroxyl or amine group. Suspensions of liposomes including these compounds have macrophage activating properties. No figure.

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