C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/26 (2006.01) A61K 31/445 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2542373
The invention relates to a compound having general formula (I), wherein: R¿1? represents either a hydrogen atom or an alkyl, cycloalkylalkyl, phenylalkyl, alkenyl, alkynyl group; X represents a hydrogen atom or one or more substituents selected from among halogen atoms and the trifluoromethyl, alkyl and alkoxy groups; and R¿2? represents a group selected from among the naphthalenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, benzimidazolyl, benzothiazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzotriazolyl, benzisothiazolyl, dihydroindolyl, pyrrolopyridinyl, furopyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl groups. The invention also relates to the use of said compound in therapeutics.
Composé de formule générale (I) dans laquelle R1 représente soit un atome d'hydrogène, soit un groupe alkyle, cycloalkylalkyle, phénylalkyle, alcényle, alcynyle, X représente un atome d'hydrogène ou un ou plusieurs substituants choisis parmi les atomes d'halogènes et les groupes trifluorométhyle, alkyle et alcoxy, R2 représente un groupe choisi parmi les les groupes naphtalényle, pyridinyle, pyrimidinyle, pyrazinyle, pyridazinyle, triazinyle, indanyle, indényle, quinoléinyle, isoquinoléinyle, quinazolinyle, quinoxalinyle, phtalazi~nyle, thiényle, furyle, pyrrolyle, imidazolyle, pyrazolyle, oxazolyle, thiazolyle, isoxazolyle, isothiazolyle, thiadiazolyle, oxadiazolyle, triazolyle, benzothiényle, benzofuryle, benzimidazolyle, benzothiazolyle, indolyle, isoindolyle, indazolyle, benzoxazolyle, benzisoxazolyle, benzotriazolyle, benzisothiazolyle, dihydroindolyle, pyrrolopyridinyle, furopyridinyle, thiénopyridinyle, imidazopyridinyle, oxazolopyridinyle, thiazolopyridinyle, pyrazolopyridinyle, isoxazolopyridinyle, isothiazolo~pyridinyle, tétrahydroquinoléinyle, tétrahydroisoquino~léinyle.
Dargazanli Gihad
Estenne-Bouhtou Genevieve
Magat Pascale
Kirby Eades Gale Baker
Sanofi-Aventis
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