C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/506 (2006.01) A61P 37/00 (2006.01) C07D 401/14 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2749837
This disclosure concerns compounds which are useful as inhibitors of protein kinase C(PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also re-lates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
La présente invention concerne des composés utilisables en tant qu'inhibiteurs de la protéine kinase C (PKC) et qui peuvent, donc, se révéler utiles dans le cadre du traitement de diverses maladies et affections à médiation ou entretenues par l'activité de la PKC. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, des procédés d'utilisation desdits composés dans le cadre du traitement de diverses maladies et affections, des procédés de préparation de ces composés et des intermédiaires utilisables dans le cadre desdits procédés de préparation.
Alvarez Salvador
Duncton Matthew
Gu Shihai
Kolluri Rao
Li Hui
Fetherstonhaugh & Co.
Rigel Pharmaceuticals Inc.
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