Derivatives of oxabispidine as neuronal nicotinic...

Details Derivatives of oxabispidine as neuronal nicotinic... Derivatives of oxabispidine as neuronal nicotinic...

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/5386 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2731790

The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with d sfunction of the central nervous s stem (CNS).

La présente invention concerne des composés de la formule (I) qui se lient à des récepteurs neuronaux de l'acétylcholine nicotinique, et qui en modulent l'activité, des processus pour préparer ces composés, des compositions pharmaceutiques contenant ces composés, ainsi que des procédés d'utilisation de ces composés pour traiter une large variété d'états et de troubles, y compris ceux associés à un dysfonctionnement du système nerveux central (CNS).

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