C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/212, 260/243
C07D 513/04 (2006.01) A61K 31/54 (2006.01)
Patent
CA 1257589
-28- ABSTRACT New derivatives of oxazinobenzothiazine-6,6-dioxide, the production thereof, and the use thereof as medicaments This invention relates to new derivatives of oxazinobenzothiazine-6,6-dioxide, to a process for the production thereof and to the use thereof as anti- inflammatory and analgesic agents. The new derivatives according to the present invention correspond to the general formula I: Image (I) wherein: R represents a linear or branched lower C1-C4 alkyl radical, in particular the methyl and ethyl radicals, X represents an oxygen atom or a sulphur atom, and Het represents a mono- or bicyclic unsaturated heterocycle containing a nitrogen heteroatom in the ortho position relative to the link between the said heterocycle and the nitrogen atom of the oxazine ring, the said heterocycle optionally -29- containing one or two other additional heteroatoms selected from nitrogen, oxygen and sulphur, and also being able to be substituted by one or two methyl radicals.
430279
Goudreau Gage Dubuc
Laboratorios Del Dr. Esteve S.a.
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