Derivatives of piperidinedione for protecting the myocardium...

Details Derivatives of piperidinedione for protecting the myocardium... Derivatives of piperidinedione for protecting the myocardium...

C - Chemistry, Metallurgy

07

D

260/278.2, 260/2

C07D 401/04 (2006.01) C07D 213/57 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1221967

- 37 - ABSTRACT OF THE DISCLOSURE The present invention relates to derivatives of piperidinedione of formula: Image (I) in which R is alkyl or forms with N a possibly substituted morpholino or piperidino group, n=2 or 3, R1, R2, R3 and R4 represent H or lower alkyl; R3 and R4 taken together may represent (CH2)m where m=4 or 5 and R2 and R3 taken together may represent (CH2)p where p=3 or 4 and in this case R1 and R4=H, R5 is H or alkyl. It also relates to a process for manufacturing the product of formula (I) and to the drugs containing a product of formula (I). The products have anti-arrhythmic activity.

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