Derivatives of pyrazoline, procedure for obtaining them and...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/06 (2006.01) A61K 31/402 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2578332

The invention relates to derivatives of general formula (I), and to their pharmaceutically acceptable salts, their stereoisomeric forms, preferably their pure enantiomeric or diastereomeric forms and their racemic forms, or a mixture thereof in any mixture ratio, and their N-oxides and the corresponding solvates or hydrates, to the processes for obtaining said derivatives and to the pharmaceutical compositions which contain them. Said derivatives are useful as anti-inflammatory and analgesic agents. In which R and R1 are different from each other and are selected from H and.

L'invention concerne des dérivés de la formule générale (I) ainsi que leurs sels pharmaceutiquement acceptables, leurs formes stéréosiomères, de préférence leurs formes énantiomères ou diastéréomères pures ainsi que leurs formes racémiques, ou un mélange de ceux-ci dans n'importe quel rapport de mélange, et leurs N-oxydes ainsi que les solvates ou hydrates correspondants, les procédés d'obtention desdits dérivés et les compositions pharmaceutiques les contenant. Lesdits dérivés sont utiles en tant qu'agents anti-inflammatoires et analgésiques.

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