Derivatives of pyridyalkylthio-benzimidazoles

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) C07D 213/61 (2006.01) C07D 213/73 (2006.01) C07D 213/74 (2006.01) C07D 213/89 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1253150

Abstract Compounds of structure (I) Image (I) and pharmaceutically acceptable salts thereof, in which R5 and R6 are the same or different and are each hydrogen, C1-6alkyl or C3-6cycloalkyl or together with the nitrogen atom to which they are attached form an azetidino, pyrrolidino, piperidino, piperazino, N-C1-4alkylpiperazino or morpholino group and one of R7 and R8 is halogen, and the other is hydrogen, halogen or C1-6alkyl; processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use as inhibitors of gastric acid secretion.

493978

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