Derivatives of quinoline as alpha-2 antagonists

Details Derivatives of quinoline as alpha-2 antagonists Derivatives of quinoline as alpha-2 antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/44 (2006.01) A61K 31/4706 (2006.01) A61K 31/4709 (2006.01) A61K 31/473 (2006.01) A61K 31/4745 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01) C07D 215/48 (2006.01) C07D 219/10 (2006.01) C07D 221/04 (2006.01) C07D 221/06 (2006.01) C07D 221/16 (2006.01) C07D 221/18 (2006.01) C07D 241/04 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2400657

The invention provides a compound of formula (I), wherein A, Ra, Rb, R1 to R5, m and t are as defined as disclosed, or a pharmaceutically acceptable salt or ester thereof, useful as alpha-2 antagonist. The compounds I can be used for the treatment of diseases or conditions wherein alpha-2 antagonists are indicated to be effective.

La présente invention concerne un composé représenté par la formule (I), dans laquelle A, Ra, Rb, R¿1? à R¿5?, m et t sont tels que définis dans les spécifications, un sel ou un ester pharmaceutiquement acceptable de ce composé, qui convient comme antagoniste alpha 2. Ces composés conviennent pour le traitement de maladies et de pathologies pour lesquelles les antagonistes alpha 2 sont réputés être efficaces.

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