Derivatives of quinolines and quinoxalines as protein...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/48 (2006.01) A61K 31/4709 (2006.01) A61K 31/498 (2006.01) A61P 35/00 (2006.01) C07D 241/44 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2725185

The invention relates to compounds of Formula (I), wherein the substituens are as defined in the specification, in free form or in the form of a pharmaceutically acceptable salt, solvate, ester, N-oxide thereof; processes for the preparation there-of; to pharmaceuticals containing such compounds, in particular for the use in one or more Protein tyrosine kinase mediated dis-eases.

Linvention concerne des composés de formule (I), dans laquelle les substituants sont tels que définis dans le mémoire, sous forme libre ou sous la forme dun de leurs sels, solvates, esters, N-oxydes pharmaceutiquement acceptables; leurs procédés de préparation; des produits pharmaceutiques renfermant de tels composés, en particulier en vue dune utilisation dans une ou plusieurs maladies médiées par des protéine tyrosine kinases.

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