Derivatives of r,s-[2-(2-hydroxyethylamino)-1-...

Details Derivatives of r,s-[2-(2-hydroxyethylamino)-1-... Derivatives of r,s-[2-(2-hydroxyethylamino)-1-...

C - Chemistry, Metallurgy

07

D

260/467.5, 260/5

C07D 513/04 (2006.01) C07D 233/42 (2006.01)

Patent

CA 1100146

ABSTRACT OF THE DISCLOSURE: New R,S-[2-(2-hydroxyethylamino)-1-phenyl] ethylamine derivatives of the general formula: Image wherein R represents hydrogen or an allyl, propargyl or benzyl radical are obtained by reacting R,S-[2-(2-hydroxyethylamino)- 1-phenyl]-ethylamine of the formula: Image with carbon disulphide to form R,S-N-[2-(2-hydroxyethylamino)-1- phenyl]-ethylamide of dithiocarbonic acid, of the formula: Image which optionally is further reacted with an allyl, propargyl or benzyl halide to yield the corresponding oster-amide. The new derivatives of the invention are valuable intermediates in the synthesis of tetramisole.

306814

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