Derivatives of streptogramins, their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/18 (2006.01) A61K 31/439 (2006.01) A61K 38/15 (2006.01) A61P 31/04 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2431560

Dérivés du groupe A des streptogramines de formule générale (I): (see formula I) dans laquelle R1 représente des radicaux cyano ou éthynyle, R2 représente un atome d'hydrogène ou un radical méthyle ou éthyle, et la liaison simple (stréréochimie 27R) ou une liaison double. Ces dérivés sont des agents antibactériens particulièrement intéressants.

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