Derivatives of substituted imidazo benzoxazin-1-one and...

C - Chemistry – Metallurgy – 07 – D

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C07D 519/00 (2006.01) A61K 31/535 (2006.01) C07D 451/00 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2114643

2114643 9325555 PCTABS00028 The invention provides derivatives of 2,3,3a,4-tetrahydro-2-azabicyclo alkyl-1H-imidazo [5,1-C][1,4]benzoxazin-1-one of general formula (I), in which inter alia R3 represents (a) or (b) wherein n is an integer or 1 or 2 and R8 is hydrogen, C1-C6 alkyl unsubstituted or substituted by phenyl, C2-C4 alkenyl, C2-C4 alkynyl, formyl or C2-C6 alkanoyl; and the pharmaceutically acceptable salts thereof, which are useful in the treatment of CNS disorders, gut motility disorders, emesis and migraine, as cognition activators, anti-drug addiction agents and analgesics.

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