Derivatives of sulindac, use thereof and preparation thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 317/44 (2006.01) A61K 31/165 (2006.01) A61K 31/395 (2006.01) A61P 35/00 (2006.01) C07D 207/04 (2006.01) C07D 211/00 (2006.01) C07D 213/04 (2006.01) C07D 241/04 (2006.01) C07D 265/30 (2006.01)

Patent

CA 2635093

Derivatives of sulindac are provided along with-pharmaceutical compositions containing them and use for precancerous conditions and treating cancer. Derivatives of sulindac are also suitable for treating chronic inflammatory conditions. A method for preparing the derivatives is also provided.

L'invention porte sur des dérivés du sulindac, sur des compositions pharmaceutiques les renfermant et sur l'utilisation de ces derniers dans les états précancéreux et dans le traitement anticancéreux. Les dérivés du sulindac conviennent également au traitement des maladies inflammatoires chroniques. L'invention concerne aussi un procédé de préparation des dérivés précités.

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