Derivatives of ureas of piperidine or pyrrolidine, their...

Details Derivatives of ureas of piperidine or pyrrolidine, their... Derivatives of ureas of piperidine or pyrrolidine, their...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4709 (2006.01) A61K 31/536 (2006.01) A61P 3/00 (2006.01) C07D 401/06 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2652852

The invention concerns compounds corresponding to formula (I) in which R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b, R4, n, i, j, o, p, q, r and X are as defined in the description. Preparation method and therapeutic use.

L'invention concerne des composés répondant à la formule (I): dans laquelle R1a, R1b, R 1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b, R4, n, j, j, o, p, q, r et X sont tels que définis dans la description et leur utilisation comme modulateurs de la 11 .beta.- hydroxystéroïde déhydrogénase de type 1 pour le traitement du syndrome métabolique ou du diabète de type 2.

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