Dermal delivery device with in situ seal

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 38/22 (2006.01) A61K 47/30 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2692884

This invention relates to a transdermal drug delivery device that comprises an active ingredient (A1) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the Al layer having a pe.pi.meter that extends beyond the perimeter of the Al layer in all directions, and an overlay comp.pi.sing a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the Al layer having a pe.pi.meter of which extends beyond the penmeter of the A1 layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the pe.pi.meter of the A1 layer to form a seal that reduces or prevents volatile component loss.

L'invention concerne un dispositif d'administration d'un médicament transdermique qui comprend une couche d'ingrédient actif (A1), ayant une surface en contact avec la peau et une surface non en contact avec la peau et comprenant un composant volatil, une doublure de libération imperméable au composant volatil adjacente à la surface en contact avec la peau de la couche A1 ayant un périmètre qui s'étend au-delà du périmètre de la couche A1 dans toutes les directions et un recouvrement comprenant un adhésif autocollant (PSA) qui n'absorbe pas le composant volatil adjacent à la surface non en contact avec la peau de la couche A1 ayant un périmètre qui s'étend au-delà du périmètre de la couche A1 dans toutes les directions, la doublure de libération et le PSA du recouvrement étant en contact avec et adhérant l'un avec l'autre autour du périmètre de la couche A1 pour former un joint qui réduit ou empêche la perte de composant volatil.

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