A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/32 (2006.01) A61L 27/38 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2648648
Improved methods for tissue engineering are provided. More particularly, methods are provided for inducing differentiation of dermis-derived cells to serve as a source of chondrocytes and associated methods of use in forming tissue engineered constructs. One example of a method is a method for inducing differentiation of cells into chondrocytes comprising providing aggrecan sensitive isolated dermis cells and seeding the cells onto an aggrecan coated surface.
La présente invention concerne des améliorations apportées à des procédés de génie histologique. L'invention concerne plus particulièrement, d'une part des procédés permettant d'induire une différenciation de cellules dérivées du derme pour servir de source de chondrocytes, et d'autre part des procédés associés convenant à la formation de constructions obtenues par génie histologique. L'invention concerne ainsi essentiellement un procédé permettant d'induire la différenciation de cellules en chondrocytes en prenant des cellules isolées de dermes et réagissant à l'aggrécan, et à ensemencer ces cellules sur une surface enduite d'aggrécan.
Athanasiou Kyriacos A.
Deng Ying
Hu Jerry
Athanasiou Kyriacos A.
Deng Ying
Gowling Lafleur Henderson Llp
Hu Jerry
William Marsh Rice University
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