Dermorphin analogs, their methods of preparation,...

C - Chemistry – Metallurgy – 07 – K

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530/7.06, 530/5.

C07K 5/107 (2006.01) A61K 38/08 (2006.01) C07K 7/06 (2006.01) C07K 14/665 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340636

Peptides are provided which are suitable for the treatment of pain and gastro-intestinal disorders, such as diarrhea, and are represented by the structure: (see fig. I) where values for the substituents and n are disclosed herein. Methods for preparing these peptides by solution and solid phase syntheses are also provided. Pharmaceutical compositions utilizing these peptides in a pharmaceutically effective amount and methods of treatment using them are provided.

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