Desaturases and process for the production of...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/82 (2006.01) A01H 5/00 (2006.01) C12N 9/02 (2006.01) C12N 15/53 (2006.01) C12P 7/64 (2006.01)

Patent

CA 2744930

The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.

La présente invention concerne des polynucléotides de Cochliobolus hétérostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina et Hyaloperonospora parasitica, qui codent pour des désaturases et qui peuvent être utilisés pour la production recombinante d'acides gras polyinsaturés. L'invention concerne en outre des vecteurs, des cellules hôtes et des organismes transgéniques non humains qui comprennent les polynucléotides selon l'invention, et les polypeptides codés par les polynucléotides. L'invention concerne en outre des anticorps contre les polypeptides selon l'invention. Enfin, l'invention concerne en outre des procédés de production pour les acides gras polyinsaturés et pour des compositions d'huile, de lipide et d'acide gras et leur utilisation en tant que médicaments, cosmétiques, denrées alimentaires, aliments pour animaux, de préférence des aliments pour poissons, ou suppléments alimentaires.

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