C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/00 (2006.01) C12N 9/10 (2006.01)
Patent
CA 2409672
The invention relates to structures and models of glycosyltransferases and ligand binding domains of glycosyltransferases, and complexes of the glycosyltransferases and ligand binding domains with ligands. The structural coordinates that define the structures and models enable the determination of homologues, the structures of polypeptides with unknown structure, and the identification of modulators of the glycosyltransferases. The invention also relates to structures and models of nucleotide-sugar donors and acceptors for the glycosyltransferases, and the design of modulators for the glycosyltransferases based on the properties of these structures and models.
L'invention concerne des structures et des modèles de glycosyltransférases ainsi que des domaines de fixation de ligands de glycosyltransférases, et des complexes des glycosyltransférases et des domaines de fixation de ligands avec des ligands. Les coordonnées structurales qui définissent les structures et les modèles permettent la détermination d'homologues, les structures de polypeptides ayant une structure inconnue, ainsi que l'identification de modulateurs des glycosyltransférases. L'invention concerne également des structures et des modèles de donneurs et d'accepteurs de nucléotides-sucre pour les glycosyltransférases, ainsi que la conception de modulateurs pour les glycosyltransférases sur la base des propriétés de ces structures et modèles.
Andre Isabelle
Kozar Tibor
Rao Mohan
Tvaroska Igor
Glycodesign Holdings Ltd.
Glycodesign Inc.
Mccarthy Tetrault Llp
LandOfFree
Designing modulators for glycosyltransferases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Designing modulators for glycosyltransferases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Designing modulators for glycosyltransferases will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1546475