Designs for non-contact laser capture microdissection

G - Physics – 01 – N

Patent

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Details

G01N 1/28 (2006.01) G01N 1/02 (2006.01)

Patent

CA 2354270

An apparatus and process for the micro juxtaposition is set forth where a selectively activatable surface is maintained spaced apart from the tissue sample and juxtaposed to the tissue sample by activation. In the typical case, activation occurs by laser radiation with the material of the activatable surface thermally expanding and bringing about the desired micro juxtaposition. The disclosed micro juxtapositioning can cause locally and microscopically pressure on tissue sample, insertion to the tissue sample, or contact of an activated or prepared surface to the tissue sample.

L'invention se rapporte à un appareil et à un procédé de micro-juxtaposition dans lequel une surface susceptible d'être activée de manière sélective est maintenue à distance d'un prélèvement tissulaire et juxtaposée à celui-ci par activation. Normalement, l'activation est effectuée à l'aide d'un rayonnement laser qui fait subir à la matière de la surface susceptible d'être activée une dilatation thermique, ce qui résulte en la micro-juxtaposition souhaitée. Ce procédé de micro-juxtaposition peut générer une pression locale et microscopique sur le prélèvement tissulaire, l'introduction dans ledit prélèvement tissulaire et le contact d'une surface activée ou préparée avec le prélèvement tissulaire.

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