Desmethylpantoprazole compositions and methods

Details Desmethylpantoprazole compositions and methods Desmethylpantoprazole compositions and methods

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2329925

Methods and compositions are disclosed utilizing desmethylpantoprazole for the treatment of ulcers in humans. Desmethylpantoprazole exhibits a lessened liability toward drug-drug interactions than pantoprazole and a more predictable dosing regimen than pantoprazole. Desmethylpantoprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.

L'invention concerne des procédés et des compositions mettant en oeuvre le déméthylpantoprazole pour traiter des ulcères chez l'homme. Comparé au pantoprazole, le déméthylpantoprazole montre une susceptibilité moindre aux interactions de médicaments et un schéma posologique plus prévisible. Le déméthylpantoprazole est également utile pour le traitement du reflux gastro-oesophagien ou d'autres affections liées à une hypersécrétion gastrique telle que le syndrome de Zollinger-Ellison.

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