Detecting compounds with liquid crystals

Details Detecting compounds with liquid crystals Detecting compounds with liquid crystals

G - Physics

01

N

G01N 21/75 (2006.01) G01N 21/21 (2006.01) G02F 1/1337 (2006.01)

Patent

CA 2440289

A device for detecting a compound in a sample includes a substrate and a self- assembled monolayer. The substrate includes a support with a metallized top surface, and the self-assembled monolayer includes an alkanethiol attached to the metallized top surface of the substrate and having a functional group that reversibly or irreversibly interacts with the compound. A liquid crystal is disposed on the self-assembled monolayer opposite the side of the self- assembled monolayer attached to the metallized top surface of the substrate. The liquid crystal includes a moiety that interacts with the functional group of the alkanethiol. When the compound is present in a sample that that contacts the self-assembled monolayer, the orientation of the liquid crystal is altered.

L'invention concerne un dispositif destiné à détecter un composé dans un échantillon et comprenant un substrat et une monocouche à autoassemblage. Le substrat comporte un support muni d'une surface supérieure métallisée, la monocouche à autoassemblage renfermant un alcanethiol fixé sur la surface supérieure métallisée du substrat et comprenant un groupe fonctionnel qui interagit réversiblement ou irréversiblement avec ledit composé. Un cristal liquide est disposé sur la monocouche à autoassemblage sur le côté opposé au côté de la monocouche à autoassemblage fixé sur la surface supérieure métallisée dudit substrat. Ce cristal liquide comprend un fragment interagissant avec le groupe fonctionnel de l'alcanethiol. Lorsque le composé est présent dans un échantillon mis en contact avec la monocouche à autoassemblage, l'orientation du cristal liquide est modifiée.

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