C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C09B 57/08 (2006.01) C09B 57/10 (2006.01) G01N 33/533 (2006.01) G01N 33/544 (2006.01) G01N 33/566 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2364324
The present invention provides a novel detecting reagent for double-stranded nucleic acid, and a method of using it to detect double-stranded nucleic acid formed by hybridization with a probe, with absolutely no labeling of the target nucleic acid. The detecting reagent for double-stranded nucleic acid of the invention is characterized by comprising, in the same molecule, a naphthalenediimide group which is intercalatable into double-stranded nucleic acid and a .beta.- diketone group capable of forming a lanthanoid metal complex.
Kondoh Yasumitsu
Matsumoto Kazuko
Nojima Takahiko
Takenaka Shigeori
Tashiro Hideo
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Riken
Waseda University
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