A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2273821
Disclosed are diagnostic and prognostic methods and kits for the detection and treatment of proliferative diseases such as cancer (e.g., ovarian cancer, breast cancer, and lymphoma). Also disclosed are therapeutics for treating proliferative diseases (and methods for identifying such therapeutics) that utilize IAP and NAIP antisense nucleic acid molecules, antibodies which specifically bind IAP and NAIP polypeptides, and compounds that reduce the biological activities of IAP and NAIP polypeptides.
Cette invention concerne des procédés de diagnostic et de prognostic ainsi que des kits de détection et de traitement de maladies prolifératives telles que le cancer (par exemple le cancer des ovaires, le cancer du sein et le lymphome). On décrit également des thérapeutiques de traitement de maladies prolifératives (et des procédés d'identification de ces thérapeutiques) dans lesquelles on utilise des molécules d'acides nucléiques antisens IAP et NAIP, des anticorps qui lient de manière spécifique des polypeptides IAP et NAIP et des composés qui réduisent l'activité biologique des polypeptides IAP et NAIP.
Baird Stephen
Korneluk Robert
Liston Peter
Mackenzie Alexander E.
Pratt Christine
Ridout & Maybee Llp
Universite D'ottawa - University Of Ottawa
LandOfFree
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