Detection and/or monitoring of synuclein-related diseases

Details Detection and/or monitoring of synuclein-related diseases Detection and/or monitoring of synuclein-related diseases

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2480466

The invention provides a method of diagnosing a synucleinopathy in a patient and also a method monitoring the effectiveness of a therapeutic agent that has been administered to a patient for the purpose of treating a synucleinopathy. The method comprises analysing a non-cerebral body fluid sample taken from the patient for the presence and/or amount of a synuclein in said sample.The synuclein may be an aggregated synuclein.

L'invention se rapporte à un procédé permettant de diagnostiquer une synucléinopathie chez un patient ainsi qu'à un procédé permettant de surveiller l'efficacité d'un agent thérapeutique qui a été administré à un patient en vue de traiter une synucléinopathie. Ce procédé consiste entre autres à analyser un échantillon liquide organique non cérébral prélevé chez le patient en vue de détecter et/ou quantifier la présence d'une synucléine dans cet échantillon. Cette synucléine peut se présenter sous la forme d'une synucléine agrégée.

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